Overview

Partners

Partnering | Overview

 

Heptares is leveraging its transformational platform to generate a broad and deep pipeline of first-in-class and best-in-class GPCR-targeted medicines. We are focused today on advancing novel drug candidates, both NCEs and antibodies, in the areas of CNS and metabolic disease.

The scope of the opportunity using the Heptares approach extends well beyond our growing pipeline. Large and untapped regions of the GPCR target universe, previously regarded as undruggable, are now tractable for rational drug discovery using the Heptares approach.

We welcome the interest from pharmaceutical and biotechnology companies seeking access to this broader GPCR target landscape through collaboration with Heptares.

Since founding, the Company has established four major collaborations:

  • Four-year collaboration with AstraZeneca and MedImmune (2011) focused on developing small molecule and antibody candidates targeting specific GPCRs linked to CNS/pain, CV/metabolic and inflammatory disorders.
  • Heptares granted Shire an exclusive licence (2012) to worldwide development and commercial rights to novel small molecule adenosine A2A receptor antagonist with best in class potential for treating CNS disorders.
  • Approximately $100 million drug discovery collaboration with Takeda (2011) focused on a GPCR linked to CNS disorders.
  • $200 million alliance with Novartis Option Fund (NOF, 2009) focused on single GPCR target of strategic interest to NOF.

For more information on outlicensing or partnering opportunities, please contact:

In the US In Europe
Dan Grau, President Barry Kenny, Chief Business Officer
dan.grau@heptares.com barry.kenny@heptares.com

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